大友 麻子/オオトモ アサコ

OTOMO Asako

助教

学位:
博士(医学)

所属学会

日本分子生物学会

日本神経化学会

日本神経科学会

主な論文・著書

  • Otomo A, et al., (2003) ALS2, a novel guanine nucleotide exchange factor for the small GTPase Rab5, is implicated in endosomal dynamics. Hum Mol Genet 12, 1671-1687.
  • Otomo A, Kunita R, Suzuki-Utsunomiya K, Mizumura H, Onoe K, Osuga H, Hadano S, Ikeda JE (2008) ALS2/alsin deficiency in neurons leads to mild defects in macropinocytosis and axonal growth. Biochem Biophys Res Commun. 370, 87-92.
  • Otomo A, Kunita R, Suzuki-Utsunomiya K, Ikeda JE, Hadano S (2011) Defective relocalization of ALS2/alsin missense mutants to Rac1-induced macropinosomes accounts for loss of their cellular function and leads to disturbed amphisome formation. FEBS Lett 585, 730-736.
  • Otomo A, Pan L, Hadano S (2012) Dysregulation of the autophagy-endolysosomal system in amyotrophic lateral sclerosis and related motor neuron diseases. Neurol Res Int. 2012, 498428.
  • Fujitani K, Otomo A, Wada M, Takamatsu N, Ito M. (2016) Sexually dimorphic expression of Dmrt1 and γH2AX in germ stem cells during gonadal development in Xenopus laevis. FEBS Open Bio 6, 276-284

メールアドレス

asako@tokai-u.jp

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