Watanabe Nobuo

論文

Usefulness of next-generation DNA sequencing for the diagnosis of urinary tract infection.

Podoplanin is indispensable for cell motility and platelet-induced epithelial-to-mesenchymal transition-related gene expression in esophagus squamous carcinoma TE11A cells.

Papaverine identified as an inhibitor of high mobility group box 1/receptor for advanced glycation end-products interaction suppresses high mobility group box 1-mediated inflammatory responses.

A pull-down and slot blot-based screening system for inhibitor compounds of the podoplanin-CLEC-2 interaction.

Cha-Koji, comprising green tea leaves fermented with Aspergillus luchuensis var kawachii kitahara, increases regulatory T cell production in mice and humans.

Detection of pathogenic bacteria in the blood from sepsis patients using 16S rRNA gene amplicon sequencing analysis.

Nitrite administration improves sepsis-induced myocardial and mitochondrial dysfunction by modulating stress signal responses.

TGF-β-induced intracellular PAI-1 is responsible for retaining hematopoietic stem cells in the niche.

A cell-based high-throughput screening assay system for inhibitor compounds of antigen presentation by HLA class II molecule.

Empyema associated with Campylobacter curvus infection.

Therapeutic potential of an orally effective small molecule inhibitor of plasminogen activator inhibitor for asthma.

Sepsis induces incomplete M2 phenotype polarization in peritoneal exudate cells in mice.

Comparative Effectiveness of Emergency Resuscitative Thoracotomy versus Closed Chest Compressions among Patients with Critical Blunt Trauma: A Nationwide Cohort Study in Japan.

Prolonged nitric oxide treatment induces tau aggregation in SH-SY5Y cells.

Neoechinulin a imparts resistance to acute nitrosative stress in PC12 cells: a potential link of an elevated cellular reserve capacity for pyridine nucleotide redox turnover with cytoprotection.

Bicarbonate plays a critical role in the generation of cytotoxicity during SIN-1 decomposition in culture medium.

Neoechinulin a impedes the progression of rotenone-induced cytotoxicity in PC12 cells.

S-nitrosation of cellular proteins by NO donors in rat embryonic fibroblast 3Y1 cells: factors affecting S-nitrosation.

Synthesis and Neuroprotective Action of Optically Pure Neoechinulin A and Its Analogs.

SIN-1 cytotoxicity to PC12 cells is mediated by thiol-sensitive short-lived substances generated through SIN-1 decomposition in culture medium.

共同研究・競争的資金等の研究課題

Study on the effectiveness of next-generation neuromuscular electrical stimulation as an alternative to physical therapy

Establishment of antibody-cocktail therapy against invading bacteria for sepsis patients

Clarification of the mechanism of functional impairment of macrophages in sepsis and development of novel therapeutics

Investigation of the mechanism of neuroprotection by neoechinulin A