Atsushi Fukuda

論文

Effect of PCDH19 missense mutations on cell-to-cell proximity and neuronal development under heterotypic conditions.

Nanosheet coating improves stability of human pluripotent stem cell culture on glass substrates.

De-erosion of X chromosome dosage compensation by the editing of XIST regulatory regions restores the differentiation potential in hPSCs

De novo DNA methyltransferases DNMT3A and DNMT3B are essential for XIST silencing for erosion of dosage compensation in pluripotent stem cells.

Deletion of lncRNA XACT does not change expression dosage of X-linked genes, but affects differentiation potential in hPSCs.

Imprinted X-chromosome inactivation impacts primitive endoderm differentiation in mouse blastocysts.

Transcriptomic features of trophoblast lineage cells derived from human induced pluripotent stem cells treated with BMP 4.

Manipulation of Xist Imprinting in Mouse Preimplantation Embryos.

Efficient production of trophoblast lineage cells from human induced pluripotent stem cells.

The serine 106 residue within the N-terminal transactivation domain is crucial for Oct4 function in mice.

Spatiotemporal dynamics of OCT4 protein localization during preimplantation development in mice.

Maintenance of Xist Imprinting Depends on Chromatin Condensation State and Rnf12 Dosage in Mice.

Chromatin condensation of Xist genomic loci during oogenesis in mice.

Generation of primitive neural stem cells from human fibroblasts using a defined set of factors.

Imbalance between the expression dosages of X-chromosome and autosomal genes in mammalian oocytes.

Deficiency of genomic reprogramming in trophoblast stem cells following nuclear transfer.

The role of maternal-specific H3K9me3 modification in establishing imprinted X-chromosome inactivation and embryogenesis in mice.

Contribution of intragenic DNA methylation in mouse gametic DNA methylomes to establish oocyte-specific heritable marks.

Epigenetically immature oocytes lead to loss of imprinting during embryogenesis.

共同研究・競争的資金等の研究課題

Generation of high-quality embryonic stem cells by new reprogramming technique and a basic research for regenerative medicine

Effect of epigenomic mutation on preimplantation development

Role of epigenetic asymmetry in embryo development