Sano Hideto

論文

Real-Time Imaging of Platelet-Initiated Plasma Clot Formation and Lysis Unveils Distinct Impacts of Anticoagulants.

Evaluation of thrombomodulin/thrombin activatable fibrinolysis inhibitor function in plasma using tissue-type plasminogen activator-induced plasma clot lysis time

Differential regulation of coagulation and fibrinolysis through thrombomodulin domain- and concentration-dependent activation of thrombin-activatable fibrinolysis inhibitor(タイトル和訳中)

Visualization of Domain- and Concentration-Dependent Impact of Thrombomodulin on Differential Regulation of Coagulation and Fibrinolysis.

止血関連因子と血管新生・動脈硬 細胞性線溶系が血管新生と創傷治癒に及ぼす影響(Hemostasis-related factors and angiogenesis/atherosclerosis Impact of cellular fibrinolytic systems on angiogenesis and wound healing)

Pre-administration of a carboxypeptidase inhibitor enhances tPA-induced thrombolysis in mouse microthrombi: Evidence from intravital imaging analysis.

Demonstration of Three Distinct High-Molecular-Weight Complexes between Plasminogen Activator Inhibitor Type 1 and Tissue-Type Plasminogen Activator.

病態とplasminogen activation調節の新機軸 トロンボモジュリン/トロンビン/TAFIを介した線溶系の時空間的な調節(Innovations in disease and regulation of plasminogen activation Spatiotemporal regulation of fibrinolysis via thrombomodulin/thrombin/TAFI system)

Fibrinolysis-resistant carbonylated fibrin detected in thrombi attached to the vascular wall of abdominal aortic aneurysms

Activated platelet-based inhibition of fibrinolysis via thrombin-activatable fibrinolysis inhibitor activation system

共同研究・競争的資金等の研究課題

The role of fibrinolytic function in the angiogenic microenvironment of wound healing using vascularized organoids

Elucidation of pathophysiology of uncontrolled bleeding due to disruption of spatiotemporal regulation of fibrinolysis using real-time imaging analysis.

Real-time imaging analysis of hemostatic thrombus stabilization and its failure

Analysis of coagulation and fibrinolytic functions and vascular endothelium-platelet interaction using disease-specific iPS cells

Understanding in spatio-temporal regulation mechanism of thrombus formation and dissolution for realization of appropriate antithrombotic therapy

Vasa Vasorum in Abdominal Aortic Aneurysm

Various reguratory mechanisms of activated-platelet' memberane-based activation of fibrinolysis.

The intrinsic roles of human PAI-1 in adipocyte differentiation and function with using patient-derived iPS cells.

Elucidation of intrinsic fibrinolytic activities potentiated vascular endothelial cells and its possibility in prophylaxis of thrombotic disease

Role of phosphatidylserine on activated platelets on tissue factor initiated blood coagulation

Generation of iPS cells from PAI-1 deficient patient and differentiation into mature cells