蟹江 治

Kanie Osamu

  • 教授
  • 学位:薬学博士

基本情報

所属

  • Undergraduate School of Engineering / Department of Applied Biochemistry
  • Graduate School of Science and Technology / Course of Science and Technology
  • Graduate School of Engineering / Course of Applied Science
  • Micro/Nano Technology Center

研究と関連するSDGs

  • Industry, Innovation and Infrastructure

詳細情報

研究キーワード

  • MS
  • LC
  • in vivo
  • Saccharomyces cerevisiae
  • mass spectrometry
  • structure
  • synthesis
  • carbohydrate
  • glycan

研究分野

  • Life sciences Functional biochemistry
  • Life sciences Bioorganic chemistry

受賞

  • Alberta Heritage Foundation Alberta Heritage Fund for Medical Research Award

論文

Temporal analysis of localization and trafficking of glycolipids.

Quality Control of Aminopropylsilylation Reaction of Silica Gel Surface

Discrimination of cellular developmental states focusing on glycan transformation and membrane dynamics by using BODIPY-tagged lactosyl ceramides.

Chemical stability of a colorimetric indicator based on sodium alginate thin film and methylene blue dye upon active oxygen species exposure

An orthogonal point of view

Stereoselective trimethylsilylation of α- and β-galactopyranoses

Structural analysis of a novel lipooligosaccharide (LOS) from Rhodobacter azotoformans

A unique structural distribution pattern discovered for the cerebrosides from starfish Asterias amurensis

Evaluation of reversed-phase nano liquid chromatography conditions by using reversed-phase thin layer chromatography based on Hansen solubility parameters for the analysis of amphiphilic glycosylsphingolipid transformations

Synthesis and structural investigation of a series of mannose-containing oligosaccharides using mass spectrometry

Reactivation of hyperglycemia-induced hypocretin (HCRT) gene silencing by N-acetyl-d-mannosamine in the orexin neurons derived from human iPS cells

Using Facebook to Announce the Latest Glyco-related Research Articles

Addressing the glycan complexity by using mass spectrometry: In the pursuit of decoding glycologic

糖は甘くはないことも:命名

Sugar is not always sweet: Naming

Endoplasmic Reticulum (ER)-Targeted, Galectin-Mediated Retrograde Transport by Using a HaloTag Carrier Protein

Diastereomeric resolution directed towards chirality determination focussing on gas-phase energetics of coordinated sodium dissociation

Non-enzymatic reaction of glycosyl oxazoline with peptides

6SLN-lipo PGA specifically catches (coats) human influenza virus and synergizes neuraminidase-targeting drugs for human influenza therapeutic potential

Introduction to the special issue on chemical glycobiology: All the aspects are important

書籍等出版物

  • Energy-resolved mass spectrometry (ERMS) of oligosaccharide
  • Stationary solid-phase reaction (SSPR) for oligosaccharide synthesis
  • Synthetic strategies
  • Pd nanoparticles
  • Carbohydrate libraries by the random glycosylation approach
  • Orthogonal strategy in oligosaccharide synthesis

講演・口頭発表等

  • 部分デオキシ化LacCerBODIPYの合成研究
  • セレブロシドリポソームがC.elegansの寿命に与える影響
  • α‐GalNAcase阻害剤のGcMAFへの効果
  • 立体特異的TMS化反応とそのグリコシド化反応への応用
  • キヒトデ(Asterias amurensis)由来セレブロシドの構造に関する研究
  • セレブロシドリポソームの消化管吸収と体内動態に関する検討
  • 合成糖脂質分子を用いた細胞膜動態の時空間解析
  • ピロリ由来α1,3‐フコース転移酵素のシアリルラクトサミン基質への特異的糖転移反応
  • “胃瘻の功罪”論の功と罪
  • Sugar is not always sweet: Naming
  • 蛍光標識化lactosyl sphingosineによる細胞膜脂質の動態解析
  • 立体特異的TMSグリコシドの合成研究
  • ピロリ由来α1,3‐フコース転移酵素のユニークな基質特異性
  • アノメリック水酸基の立体特異的TMS化反応
  • 蛍光標識糖脂質をプローブとした細胞内膜系の動態解析
  • 多価性効果を利用した糖‐タンパク質間相互作用を基盤とするオーガニックフレームワークの創成研究
  • 一分子修飾探針によるUDP‐グルコース:糖タンパク質グルコース転移酵素(UGGT)1の直接AFM観察
  • 蛍光標識化スフィンゴ糖脂質による細胞内オルガネラの動態解析
  • 糖‐タンパク質間結合を基盤とするオーガニックフレームワークの創成研究:LacNAc含有環状ペプチドの合成研究
  • デオキシ化糖を含む蛍光標識化糖脂質の化学合成研究

所属学会

  • FCCA(Forum:Carbohydrates Coming of Age)
  • American Chemical Society

産業財産権

  • Azasugar compound
  • Medicaments comprising sialic acid derivatives as active ingredients

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