今川 和彦

今川 和彦

  • 教授
  • 学位:Ph.D

基本情報

所属

  • Graduate School of Bioscience / Course of Bioscience
  • Graduate School of Agriculture / Course of Agricultural Sciences
  • The Research Institute of Agriculture

ジャンル

  • Biotechnology

詳細情報

研究キーワード

  • Genetics
  • Molecular biology
  • Mammalian evolution
  • Implantation/placentation
  • Reproduction

研究分野

  • Life sciences Veterinary medicine
  • Life sciences Veterinary medicine
  • Life sciences Veterinary medicine

委員歴

  • The Japanese Society of Animal Reproduction Advisory Board

論文

A target enrichment high throughput sequencing system for characterization of BLV whole genome sequence, integration sites, clonality and host SNP.

Retrotransposons on the development and diversity of placenta

Peptidoglycan disrupts early embryo-maternal crosstalk via suppression of ISGs expression induced by interferon-tau in the bovine endometrium.

Genetic variation in Japanese Holstein cattle for EBL development.

Sensing sperm via maternal immune system: a potential mechanism for controlling microenvironment for fertility in the cow.

Emerging Role of Extracellular Vesicles in Embryo-Maternal Communication throughout Implantation Processes.

Roadmap to pregnancy in the first 7 days post-insemination in the cow: Immune crosstalk in the corpus luteum, oviduct, and uterus.

IFNT-independent effects of intrauterine extracellular vesicles (EVs) in cattle.

Promoting Roles of Embryonic Signals in Embryo Implantation and Placentation in Cooperation with Endocrine and Immune Systems.

Effects of miR-98 in intrauterine extracellular vesicles on maternal immune regulation during the peri-implantation period in cattle.

Novel crosstalk between Vps26a and Nox4 signaling during neurogenesis.

Increasing Bovine leukemia virus (BLV) proviral load is a risk factor for progression of Enzootic bovine leucosis: A prospective study in Japan.

TLR2/4 signaling pathway mediates sperm-induced inflammation in bovine endometrial epithelial cells in vitro.

Day-7 embryos generate an anti-inflammatory immune response in peripheral blood immune cells in superovulated cows.

Evidence that interferon-tau secreted from Day-7 embryo in vivo generates anti-inflammatory immune response in the bovine uterus.

Integration of molecules to construct the processes of conceptus implantation to the maternal endometrium.

Regulation of human trophoblast cell syncytialization by transcription factors STAT5B and NR4A3

Down-regulation of transcription factor OVOL2 contributes to epithelial-mesenchymal transition in a noninvasive type of trophoblast implantation to the maternal endometrium.

Oviduct epithelium induces interferon-tau in bovine Day-4 embryos, which generates an anti-inflammatory response in immune cells.

Exchange protein directly activated by cAMP (EPAC) promotes transcriptional activation of the decidual prolactin gene via CCAAT/enhancer-binding protein in human endometrial stromal cells.

書籍等出版物

  • Genetics and Animal Breeding
  • Regulation of cytokines during peri-implantation periods in ruminant ungulates. (共著)
  • Regulation of interferon-tau expression. (共著)
  • Identification and cellular localization of human placental interferon. (共著)
  • Cytokines as mediators of pregnancy specific interferon, ovine trophoblast protein-1. (共著)
  • The polypeptides and genes of ovine and bovine trophoblast protein-1. (共著)
  • Embryonic mediators of maternal recognition of pregnancy. (共著)
  • Embryonic interferons and maternal recognition of pregnancy. (共著)
  • Interferons and maternal recognition of pregnancy. (共著)

講演・口頭発表等

  • Integration of molecules to construct the processes of conceptus implantation to the maternal endometrium

担当経験のある科目

  • Animal Hygene
  • Animal Production in the world

所属学会

  • KANTO SOCIETY OF ANIMAL SCIENCE
  • JAPAN SOCIETY OF FERTILIZATION AND IMPLANTATION
  • THE JAPAN ENDOCRINE SOCIETY
  • JAPANESE SOCIETY OF VETERINARY SCIENCE
  • JAPANESE SOCIETY OF ANIMAL SCIENCE
  • SOCIETY FOR REPRODUCTION AND DEVELOPMENT
  • The Japanese Society of Animal Reproduction

Works(作品等)

Mechanisms of development in Crohn's and Johes diseases

Use of Chemokine in enhancing reproductive efficiency

Development of early pregnancy detection method

共同研究・競争的資金等の研究課題

IFN expression and viral resistant animals

Regulation of interferon-tau gene expression

Biology of implantation : Prevention of embryonic loss

産業財産権

  • Human trophoblast derived interferon and methods of use. 特許US
  • Use of interferons of the alpha family to enhance fertility in mammals 特許US07/312,853
  • Detergent composition providing rinse cycle suds control. 特許US/23.01.86/US821669

ResearchMapへ移動します

Inquiries about coverage or research

Inquiries about coverage

Public Affairs Division Public Affairs and Communications Department

Tel. 0463-58-1211(Main) Fax. 0463-50-2215