Kawakami Takashi

論文

SELEX-discovered aptamer that inhibits cellular interleukin-17/interleukin-17 receptor interaction and antagonizes interleukin-17 signaling

Growth optimization of single-phase novel colloidal perovskite Cs3Bi2I9 nanocrystals and Cs3Bi2I9@SiO2 core-shell nanocomposites for bio-medical application

In vitro display evolution of unnatural peptides spontaneously cyclized via intramolecular nucleophilic aromatic substitutions

Discovery of IL-5-binding unnatural cyclic peptides from multiple libraries by directed evolution

Artificial aptamer that inhibits interleukin-23/interleukin-23 receptor interaction discovered via SELEX

A human epidermal growth factor receptor 3/heregulin interaction inhibitor aptamer discovered using SELEX

In vitro selection generates RNA aptamer that antagonizes PCSK9–LDLR interaction and recovers cellular LDL uptake

In vitro selection of an RNA aptamer yields an interleukin-6/interleukin-6 receptor interaction inhibitor

In vitro display evolution of IL-6R-binding unnatural peptides ribosomally initiated and cyclized with m-(chloromethyl)benzoic acid

Directed evolution of dibenzocyclooctyne-reactive peptide tags for protein labeling

In vitro display evolution of the PURE system-expressed TNFα-binding unnatural cyclic peptide containing an N-methyl-d-amino acid

Directed Evolution of a Cyclized Peptoid-Peptide Chimera against a Cell-Free Expressed Protein and Proteomic Profiling of the Interacting Proteins to Create a Protein-Protein Interaction Inhibitor

DIVERSE System: De Novo Creation of Peptide Tags for Non-enzymatic Covalent Labeling by In Vitro Evolution for Protein Imaging Inside Living Cells

Incorporation of electrically charged N-alkyl amino acids into ribosomally synthesized peptides via post-translational conversion

Patch cloning method for multiple site-directed and saturation mutagenesis

Extensive Reprogramming of the Genetic Code for Genetically Encoded Synthesis of Highly N-Alkylated Polycyclic Peptidomimetics

In Vitro Selection of Multiple Libraries Created by Genetic Code Reprogramming To Discover Macrocyclic Peptides That Antagonize VEGFR2 Activity in Living Cells

TRAP Display: A High-Speed Selection Method for the Generation of Functional Polypeptides

Genetically encoded libraries of nonstandard peptides

Natural Product-Like Macrocyclic N-Methyl-Peptide Inhibitors against a Ubiquitin Ligase Uncovered from a Ribosome-Expressed De Novo Library