Ibrahim Abd Aziz

論文

Mitochondrial Electron Transport Chain Complex II Dysfunction Causes Premature Aging of Hematopoietic Stem Cells

Plasminogen activator inhibitor type-1 is a negative regulator of hematopoietic regeneration in the adipocyte-rich bone marrow microenvironment

IMiDs uniquely synergize with TKIs to upregulate apoptosis of Philadelphia chromosome-positive acute lymphoblastic leukemia cells expressing a dominant-negative IKZF1 isoform

Inhibition of plasminogen activator inhibitor-1 attenuates against intestinal fibrosis in mice

Targeting of plasminogen activator inhibitor-1 activity promotes elimination of chronic myeloid leukemia stem cells

Blockade of plasminogen activator inhibitor-1 empties bone marrow niche sufficient for donor hematopoietic stem cell engraftment without myeloablative conditioning

TGF-β–induced intracellular PAI-1 is responsible for retaining hematopoietic stem cells in the niche

Inhibition of Plasminogen Activator Inhibitor Type-1 Activity Enhances Rapid and Sustainable Hematopoietic Regeneration

Accumulation of oxidative DNA damage restricts the self-renewal capacity of human hematopoietic stem cells

共同研究・競争的資金等の研究課題

To Elucidate the Regulation Mechanism of Hematopoietic Stem Cell's Mobility

Blockade of PAI-1 eliminates leukemic stem cells

Establishment of new method for leukemia therapy by targeting fibrinolytic pathway

Establishment of hematopoietic regeneration by the novel molecular targeting drug