Kimura Minoru

論文

Potential UV-Protective Effect of Freestanding Biodegradable Nanosheet-Based Sunscreen Preparations in XPA-Deficient Mice.

Somatic mutations in oral squamous cell carcinomas in 98 Japanese patients and their clinical implications.

Deletion of lncRNA XACT does not change expression dosage of X-linked genes, but affects differentiation potential in hPSCs.

Analysis of HRAS mutations in Japanese patients with oral squamous cell carcinoma

AMBRA1 controls antigen-driven activation and proliferation of naïve T cells.

Alopecia areata susceptibility variant in MHC region impacts expressions of genes contributing to hair keratinization and is involved in hair loss.

New PCNT candidate missense variant in a patient with oral and maxillofacial osteodysplasia: a case report.

日本人口腔扁平上皮癌に対する遺伝子変異解析(Genomic mutational analysis of Japanese oral squamous cell carcinoma)

Alopecia areata susceptibility variant identified by MHC risk haplotype sequencing reproduces symptomatic patched hair loss in mice.

A mutation in NOTCH1 ligand binding region detected in patients with oral squamous cell carcinoma reduces NOTCH1 oncogenic effect

AMBRA1 is involved in T cell receptor-mediated metabolic reprogramming through an ATG7-independent pathway.

The intrauterine environment affects learning ability of Tokai high avoider rat offspring derived using cryopreservation and embryo transfer-mediated reproduction

Microneedle pH Sensor: Direct, Label-Free, Real-Time Detection of Cerebrospinal Fluid and Bladder pH

Preparation of clinically useful sennoside-reduced rhubarb

Abnormal gait, reduced locomotor activity and impaired motor coordination in Dgcr2-deficient mice

Identification of a novel HLA-C allele, HLA-C*03:313, in a Japanese individual.

共同研究・競争的資金等の研究課題

Expression characteristics of Sez12 gene, the murine homolog of DGCR2, in chondrocytes from 22q11.2 deletion syndrome model with knocked-in GFP

Development of comprehensive identification of spontaneous mutations based on whole genome sequencing applicable for the assessment of low-dose mutagens.

Establishment of assessment method for onset risk of sick house syndrome based on skin metabolism

Influences of stresses to motor learning

Elucidation of the mechanism of renal dysfunction improvement by Kampo treatment

The Sez12, mouse homolog of DGCR2 gene encoding within 22q11.2, contributes to enchondral ossification in skull base

Functional analysis of NOTCH1 variants

Oral cancer model of functional mutations in NOTCH1 and HRAS

Towards the diagnosis method for the toxicity of organophosphorus

Developing the Universal iPS cell lines using genetic engineering system

Molecular analysis of mast cell activation in mouse models for autoinflammatory syndromes and its use for anti-inflammatory drug development

Sez12 gene contributes to the chondrocytes differentiation by modulating TGF-ß signaling during postnatal maxillofacial development.

Analysis for the function of the candidate gene of Sick House Syndrome and development of disease model mouse

HLA genome diversity analyses by resequencing

Construction of molecular basis and clinical application of Kampo medicine

Analysis of the inflammatory mechanisms caused by the Ali18 mutation in molecular and cellular levels

Molecular analysis of craio-facial abnormalities found in the Sez12 knockout mice

Molecular pathology for functional differentiation of human pituitary adenomas : New development of NOTCH signaling pathway.