Gondo Yoichi

論文

DETECTION OF TRANSGENERATIONAL GENETIC EFFECTS BASED ON WHOLE-GENOME SEQUENCING IN THE MOUSE MODEL

Early embryonic mutations reveal dynamics of somatic and germ cell lineages in mice.

Assessing reproducibility of inherited variants detected with short-read whole genome sequencing

Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis

A Comprehensive Mouse Transcriptomic BodyMap across 17 Tissues by RNA-seq

Illegitimate translation causes unexpected gene expression from on-target out-of-frame alleles created by CRISPR-Cas9

Dose-dependent de novo germline mutations detected by whole-exome sequencing in progeny of ENU-treated male gpt delta mice

Estimation of the frequency of inherited germline mutations by whole exome sequencing in ethyl nitrosourea-treated and untreated gpt delta mice

A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium

The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis

Do Long and Highly Conserved Noncoding Sequences in Vertebrates Have Biological Functions?

Timeline - Trends in large-scale mouse mutagenesis: from genetics to functional genomics

Behavioral phenotypes of Disc1 missense mutations in mice

Molecular characterization of ENU mouse mutagenesis and archives

Human megasatellite DNA RS447: Copy-number polymorphisms and interspecies conservation

A novel positive detection system of in vivo mutations in rpsL (strA) transgenic mice

p53-dependent apoptosis suppresses radiation-induced teratogenesis

THEORETICAL BASIS OF ONE-DIMENSIONAL GENOME SCANNING - A DIRECT METHOD TO IDENTIFY THE SITE OF A MUTATION

SIZE-SELECTED GENOMIC LIBRARIES - THE DISTRIBUTION AND SIZE-FRACTIONATION OF RESTRICTED GENOMIC DNA FRAGMENTS BY GEL-ELECTROPHORESIS

GENE REPLACEMENT OF THE P53 GENE WITH THE LACZ GENE IN MOUSE EMBRYONIC STEM-CELLS AND MICE BY USING 2 STEPS OF HOMOLOGOUS RECOMBINATION

HIGH-FREQUENCY GENETIC REVERSION MEDIATED BY A DNA DUPLICATION - THE MOUSE PINK-EYED UNSTABLE MUTATION

THE MOUSE PINK-EYED DILUTION GENE - ASSOCIATION WITH HUMAN PRADER-WILLI AND ANGELMAN SYNDROMES

GENETIC AND MOLECULAR ANALYSIS OF RECESSIVE ALLELES AT THE PINK-EYED DILUTION (P) LOCUS OF THE MOUSE

DIRECT MOLECULAR-IDENTIFICATION OF THE MOUSE PINK-EYED UNSTABLE MUTATION BY GENOME SCANNING

Works（作品等）

The functional study of genes for Disc1, Srr, CBP, NCS-1 and Rtn4r at the organismal level.

The functional study of the sacsin gene at the organismal level.

Analysis of mutant mice for catecholamin-related genes.

The functional study of the T2BP gene (MMU03H1) at the organismal level.

The functional study of genes for Dock1 (MMU07F5) and Ephrin-A6 (MMU16) at the organismal level.

The functional study of the DmrtC2 (MMU07A3) gene at the organismal level.

The functional study of genes for Rab5a (MMU17D) and Rabggtb (MMU03H4) gene at the organismal level.

共同研究・競争的資金等の研究課題

High-throughput and precision analysis of biological effects of low-dose-rate radiation.

Analysis of radiation effects based on high-sensitive detection of mutations in mice and cells exposed to protracted low-dose-rate irradiation.

Development of comprehensive identification of spontaneous mutations based on whole genome sequencing applicable for the assessment of low-dose mutagens.

Detection of mouse germline mutations by ultra-throughput genomic analyses and development of the risk assessment system for low-dose mutagens

High-throughput development of disease model mice by using next-generation technologies.

Development of mutant mice carrying base-substitutions in target genes.

EVOLUTION OF MEGASATELLITE DNA.

STRUCTURAL ANALYSIS OF RS447 MEGASATELLITE DNA.

Studies of Somatic Mutation Frequencies and Spectra with a Sensitive and Efficient Detection Method by Using Transgenic Mice.

THE STUDY OF HOMOLOGOUS RECOMBINATION AND GENE REPAIR IN MOUSE SOMATIC CELLS.