石野 知子

Ishino(Kaneko) Tomoko

  • 教授
  • 学位:理学博士

基本情報

所属

  • Undergraduate School of Medicine / Faculty of Nursing

ジャンル

  • Animals And Plants
  • Biotechnology

研究と関連するSDGs

  • Good Health and Well-Being

詳細情報

研究キーワード

  • Epigeneitics
  • Genome imprinting
  • Molecular Embryology

研究分野

  • Life sciences Developmental biology
  • Life sciences Molecular biology
  • Life sciences Systems genomics
  • Life sciences Genomics

論文

Targeting retrovirus-derived Rtl8a and 8b causes late onset obesity and neurodevelopmental defects

Retrovirus-derived RTL5 and RTL6 genes are novel constituents of the innate immune system in the eutherian brain

PEG10 viral aspartic protease domain is essential for the maintenance of fetal capillary structure in the mouse placenta.

HERV-Derived Ervpb1 Is Conserved in Simiiformes, Exhibiting Expression in Hematopoietic Cell Lineages Including Macrophages.

Deficiency and overexpression of Rtl1 in the mouse cause distinct muscle abnormalities related to Temple and Kagami-Ogata syndromes.

Severe damage to the placental fetal capillary network causes mid- to late fetal lethality and reduction in placental size in Peg11/Rtl1 KO mice

An LTR Retrotransposon-Derived Gene Displays Lineage-Specific Structural and Putative Species-Specific Functional Variations in Eutherians

Mammalian-specific genomic functions: Newly acquired traits generated by genomic imprinting and LTR retrotransposon-derived genes in mammals

Cognitive Function Related to the Sirh11/Zcchc16 Gene Acquired from an LTR Retrotransposon in Eutherians

A trans-homologue interaction between reciprocally imprinted miR-127 and Rtl1 regulates placenta development

Double strand break repair by capture of retrotransposon sequences and reverse-transcribed spliced mRNA sequences in mouse zygotes

Sirh7/Ldoc1 knockout mice exhibit placental P4 overproduction and delayed parturition

Induction of the G2/M transition stabilizes haploid embryonic stem cells

Active DNA demethylation is required for complete imprint erasure in primordial germ cells

Identification of a Novel PNMA-MS1 Gene inMarsupials Suggests the LTR Retrotransposon-Derived PNMA leGenes Evolved Differently inMarsupials and Eutherians

Gene expression changes induced by intracitoplasmic sperm injection

The origin and evolution of genomic imprinting and viviparity in mammals

The evolution of the placenta and viviparity is related to LTR retrotransposon-derived genes in mammals

Evolution of viviparity and genomic imprinting in mammals by retrotransposons

Gene Expression Profile Normalization in Cloned Mice by Trichostatin A Treatment

書籍等出版物

  • Subtraction-hybridization methid for the identification of imprinted genes.(joitly worked)
  • Genomic imprinted genes in human and mice. (共著)
  • Systematic approaches for identifing imprinted genes

Works(作品等)

Systematic screening and molecular mechanism of imprinted genes

Mammalian specific genomic function

共同研究・競争的資金等の研究課題

Mechanism of Mammalian Specific Acquired Genes in Brain

The function of evolutionarily conserved retrotransposon-derived genes in mammalian development.

Genomic imprinting in a marsupial.

Origin of genome imprinting in mammals

Molecular Mechanism of Genomic Imprinting

Gene expression of the mouse reproduced without meiotic division.

Genomic Imprinting and Genetic Disease in Mammals

Analysis of Peg and Meg Transgenic mice.

Analysis of Imprinted Genes Expressed in the Brain.

産業財産権

  • Mouse models of type (]G0002[) diabetes.

ResearchMapへ移動します

Contact Us

Inquiries about coverage

Public Affairs Division Public Affairs and Communications Department

Tel. 0463-63-4670(direct dialing)