Okamoto Akihiro

論文

Boundary of the nucleotide-binding domain of Streptococcus ComA based on functional and structural analysis.

Crystal Structure of the Peptidase Domain of Streptococcus ComA, a Bifunctional ATP-binding Cassette Transporter Involved in the Quorum-sensing Pathway

Structural Insights into the Enzymatic Mechanism of Serine Palmitoyltransferase from Sphingobacterium multivorum

Structural biology of sphingolipid synthesis

Structure-based functional identification of a novel heme-binding protein from Thermus thermophilus HB8

Dual substrate recognition of aminotransferases

Increased rigidity of domain structures enhances the stability of a mutant enzyme created by directed evolution

Crystal structure of a family 4 Uracil-DNA glycosylase from Thermus thermophilus HB8

Cocrystallization of a mutant aspartate aminotransferase with a C5-dicarboxylic substrate analog: Structural comparison with the enzyme-C4-dicarboxylic analog complex

Redesigning the substrate specificity of an enzyme by cumulative effects of the mutations of non-active site residues

The active site of Paracoccus denitrificans aromatic amino acid aminotransferase has contrary properties: Flexibility and rigidity

Aromatic L-amino acid decarboxylase: Conformational change in the flexible region around Arg334 is required during the transaldimination process

Crystal structures of Paracoccus denitrificans aromatic amino acid aminotransferase: A substrate recognition site constructed by rearrangement of hydrogen bond network

Paracoccus denitrificans aromatic amino acid aminotransferase: A model enzyme for the study of dual substrate recognition mechanism

An aspartate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus HB8

X-RAY CRYSTALLOGRAPHIC STUDY OF PYRIDOXAL 5'-PHOSPHATE-TYPE ASPARTATE AMINOTRANSFERASES FROM ESCHERICHIA-COLI IN OPEN AND CLOSED-FORM

CONSTRUCTION OF AMINOTRANSFERASE CHIMERAS AND ANALYSIS OF THEIR SUBSTRATE-SPECIFICITY

SYNTHESIS AND PROPERTIES OF SOME STERICALLY PROTECTED 2-(1- AND 2-AZULENYL)-1-PHOSPHAETHENES

SITE-DIRECTED MUTAGENESIS OF ESCHERICHIA-COLI ASPARTATE-AMINOTRANSFERASE - ROLE OF TYR70 IN THE CATALYTIC PROCESSES

共同研究・競争的資金等の研究課題

Analysis of Enzymatic Reaction mechanism