Yasuda Shin

教授
学位：博士（農学）

基本情報

所属

Undergraduate School of Agriculture / Department of Food and Life Sciences
Undergraduate School of Agriculture / Department of Bioscience
Graduate School of Bioscience / Course of Bioscience
Graduate School of Agriculture / Course of Agricultural Sciences

研究と関連するSDGs

詳細情報

研究キーワード

Health Food
Functional Food Science
Drug Metabolism Chemistry
Food Biochemistry
Drug Metabolism

研究分野

Life sciences Food sciences
Life sciences Pharmacology

委員歴

Biotechnological Research Development Association Committee Member
Japan Society for Bioscience, Biotechnology, and Agrochemistry, JSBBA Advisory board member
Japanese Association of Food Science and Risk Analysis Committee Member
Japanese Society for Food Science and Technology Committee Member
Japanese Society of Nutrition and Food Science Committee Member

受賞

Young Researcher Encouragement Award Study on Food Functions and Bioavailablity using Functional Food Evaluation Techniques
2011 5th International Conference on Food Factors (ICoFF 2011) Young Investigator Award Antiproliferative activity and induction of apoptotic DNA damage by highly-lipolyzed goat cheeses

論文

Exploring the potential of functional foodstuffs: Initial assessment of grape leaves and immature fruits cultivated in Minamiaso, Aso, Kumamoto, Japan

Determination of acetaminophen O-sulfate and tyrosine O-sulfate by high-performance liquid chromatography with UV detection

Investigation of radical scavenging effects of acetaminophen, p-aminophenol and their O-sulfated conjugates.

Total phenolic content and antioxidant activity of perilla pomace produced in Kumamoto: Comparative evaluation with ground sesame seeds

Chemical Synthesis of Acetaminophen O-Sulfate

Investigation of Total Polyphenol Content, Antioxidant Activity, and Carbohydrate-hydrolyzing Enzyme Inhibition of Yacon Leaves among Four Domestic Cultivars and a Peru Line for over Four Years

Development of a unique processed food using roasted Jerusalem Artichoke (Helianthus tuberosus) cultivated at Kumamoto-Minamiaso in Japan

Effects of indole and indoxyl on the intracellular oxidation level and phagocytic activity of differentiated HL-60 human macrophage cells

Investigation of the effects of indoxyl sulfate, a uremic toxin, on the intracellular oxidation level and phagocytic activity using an HL-60-differentiated human macrophage cell model.

Effect of heat processing with pressure on antioxidant activity of Makomotake cultivated at Minamiaso, Aso, Kuamamoto in Japan

Increased phenolic content and antioxidant capacity of the heated leaves of yacon (Smallanthus sonchifolius).

Effect of heat processing with pressure on inulin contents and antioxidant capacity of Jerusalem Artichoke (Helianthus tuberosus) cultivated at Kumamoto-Minamiaso in Japan

Optimization of hot-water extraction of dried yacon herbal tea leaves: Enhanced antioxidant activities and total phenolic content by response surface methodology

Radical scavenging effects of 1-naphthol, 2-naphthol, and their sulfate-conjugates.

Unique antioxidant effects of herbal leaf tea and stem tea from Moringa oleifera L. especially on superoxide anion radical generation systems.

Total polyphenol and rutin contents, and antioxidant capacity of native Kugino-zairai buckwheat cultivated in Kumamoto-Aso area: Comparison with rutin-rich SunRutin and commercial Kitawase-soba cultivars

Effect of two-step heat processing on the antioxidant activity and phenolic constituents of leaves from yacon cultivated in Kumamoto

Effects of Hot-water Extract of Herbal Tea Leaves from Yacon (Smallanthus sonchifolius): Lipoxygenase Inhibition and Suppression on Nitric Oxide Generation in RAW264.7 Mouse Macrophage-like Cells

In vitro α-glucosidase and α-amylase inhibitory effects of herbal tea leaves from Yacon (Smallanthus sonchifolius)

In vitro anti-inflammatory effects of edible Igusa soft rush (Juncus effusus L.) on lipoxygenase, hyaluronidase, and cellular nitric oxide generation assays: Comparison with Matcha green tea (Camellia sinensis L.)

In Vitro α-Amylase and α-glucosidase inhibitory effects of edible soft rush (Juncus effusus L.)

Antioxidant Effects of Herbal Tea Leaves from Yacon (Smallanthus sonchifolius) on Multiple Free Radical and Reducing Power Assays, Especially on Different Superoxide Anion Radical Generation Systems

Inhibitory effects of the ethyl acetate extract from bulbs of Scilla scilloides on lipoxygenase and hyaluronidase activities.

Homoisoflavones as the antioxidants responsible from bulbs of Scilla scilloides.

Anti-inflammatory and antioxidative effects of a methanol extract from bulbs of Scilla scilloides.

Determination of 1,1-diphenyl-2-picrylhydrazyl radical scavenging capacity and total phenolic content in four different igusa cultivars in Japan

Induction of Nitric Oxide Generation by Various Cow Milk Cheeses in RAW264.7 Mouse Macrophage-like Cells

Effect of highly lipolyzed goat cheese on HL-60 human leukemia cells: Antiproliferative activity and induction of apoptotic DNA damage

Scavenging effects of commercial goat cheeses on hydrogen peroxide and superoxide anion radical assays

Sulfation of chlorotyrosine and nitrotyrosine by human lung endothelial and epithelial cells: Role of the human SULT1A3

Effects of highly ripened cheeses on HL-60 human leukemia cells: Antiproliferative activity and induction of apoptotic DNA damage

Concerted action of the cytosolic sulfotransferase, SULT1A3, and catechol-O-methyltransferase in the metabolism of dopamine in SK-N-MC human neuroblastoma cells

A novel hydroxysteroid-sulfating cytosolic sulfotransferase, SULT3 ST3, from zebrafish: Identification, characterization, and ontogenic study

Cigarette smoke toxicants as substrates and inhibitors for human cytosolic SULTs

Hydroxylated serotonin and dopamine as substrates and inhibitors for human cytosolic SULT1A3.

Generation and release of nitrotyrosine O-sulfate by HepG2 human hepatoma cells upon SIN-1 stimulation: Identification of SULT1A3 as the enzyme responsible

Identification of novel hydroxysteroid-sulfating cytosolic SULTs, SULT2 ST2 and SULT2 ST3, from zebrafish: Cloning, expression, characterization, and developmental expression

Tissue-specific distribution of genistein, daidzein and bisphenol A in male Sprague-Dawley rats after intragastric administration

Identification of a novel thyroid hormone-sulfating cytosolic sulfotransferase, SULT1 ST5, from zebrafish: Molecular cloning, expression, characterization and ontogenic study

Identification of a novel estrogen-sulfating cytosolic SULT from zebrafish: Molecular cloning, expression, characterization, and ontogeny study

Oral contraceptives as substrates and inhibitors for human cytosolic SULTs

Suppressive effects of ascorbate derivatives on ultraviolet-B-induced injury in HaCaT human keratinocytes

Simultaneous determination of isoflavones and bisphenol A in rat serum by high-performance liquid chromatography coupled with coulometric array detection

Oral administration of soy isoflavones and determination of serum isoflavone levels in Sprague-Dawley rats

Dietary Effect of Ginkgo Biloba and Bamboo Extract Powders on Lipid Metabolism and Immune Function of Sprague-Dewley Rats

書籍等出版物

Handbook of cheese in health: Production, nutrition and medical sciences
Handbook on Cheese: Production, Chemistry and Sensory Properties (Agriculture Issues and Policies: Food Science and Technology)

講演・口頭発表等

Exploring antioxidant properties of yacon leaf herbal tea as a health food in Japan
Profiling study of excellent cultivars and lines of domestic yacon leaves with high polyphenol content and antioxidant activity
On the suppression of HL-60 human leukocyte cell growth by indoxyl sulfate: regulatory effect with a representative antioxidant, Trolox
Antiproliferative effect of a resin glycoside fraction from Calystegia japonica on HL-60 human promyelocytic leukemia cells
Effect of p-cresyl sulfate on the intracellular oxidation levels of HL-60-differentiated macrophage cells under oxidative stress: concerted actions with hydrogen peroxide and nitric oxide
Determination of acetaminophen O-sulfate and tyrosine O-sulfate by high-performance liquid chromatography with UV detection
On the multifunctional properties of 37 different soft rush grown in Japan: in vitro evaluation and multivariate analysis
Cholinesterase inhibition by hot-water extracts from 21 different leaves of yacon cultivated in 2022 in Aso area
Investigation of antioxidant activities of Phase-II sulfated compounds. In Symposium 5: Phase II conjugation reactions involved in the regulation of biologically active molecules
Antioxidant effects of herbal tea from yacon leaves as a healthy drink in Japan
Investigation of Radical Scavenging Effects of Acetaminophen, p-Aminophenol and Their O-Sulfated Conjugates
Investigation of Total Polyphenol Content, Antioxidant Activity, and Carbohydratehydrolyzing Enzyme Inhibition of Yacon Leaves among Four Domestic Cultivars and a Peru Line for over Four Years
Investigation of the Effect of Indoxyl Sulfate, a Uremic Toxin, on the Phagocytic Activity Using an HL-60-differentiated Human Macrophage Cell Model
Development of Chemical Synthesis for Acetaminophen O-Sulfate
Investigation of the Effect of Indoxyl Sulfate, a Uremic Toxin, on the Intracellular Oxidation Level Using an HL-60-differentiated Human Macrophage Cell Model
Increased Phenolic Parameters;Antioxidant Capacities in;Heated Leaves of Yacon;Smallanthus sonchifolius)
On the Promotion of Cellular Oxidation and Suppression of Phagocytosis by Indoxyl Sulfate, an Uremic Toxin from Tryptophan, in Human Macrophage Model Cells
On hot-water extraction of Japanese yacon herbal tea intended for drinking: optimization of higher antioxidant activities and total phenol content by response surface methodology
Challenge of Acetaminophen O-Sulfate Synthesis by an Established Method for Organic Synthesis of Tyrosine O sulfate
Evaluation of Antioxidant Activity and Human Serum Albumin Binding Capacity of Uremic Toxin Indoxyl Sulfate and Its Related Metabolites
Total Phenol Content and Different Antioxidant Activities of Yacon Herbal Tea: Optimization of Extraction Conditions by Multi-factor Response Surface Methodology
In vitro α-Glucosidase and α-Amylase Inhibitory Effects of the Hot-water Extract of Tea Leaves from Camellia Japonica Cultivated in Kumamoto-Aso Area
Effect of Two-step Heat Processing on the Antioxidant Activity and Phenolic parameters of Leaves from Yacon Cultivated in Kumamoto, Japan
Antioxidant effects of herbal tea leaves from Yacon (Smallanthus sonchifolius) on multiple free radical assays (Invited)
Comparison of phenolic parameters and inhibitory effects of yacon leaves from different varieties on carbohydrate digestive enzymes
Inhibitory effect of 4-methylumbelliferyl sulfate on superoxide anion radical generation assays
Inhibitory effect of p-nitrophenyl O-sulfate on the O2- radical production
Japan’s Functional Food Trend in 21th Century (Invited)