Yasuda Shin
- 教授
- 学位：博士（農学）
基本情報
所属
- Undergraduate School of Agriculture / Department of Food and Life Sciences
- Graduate School of Bioscience / Course of Bioscience
- Graduate School of Agriculture / Course of Agricultural Sciences
研究と関連するSDGs
詳細情報
研究キーワード
- Health Food
- Functional Food Science
- Drug Metabolism Chemistry
- Food Biochemistry
- Drug Metabolism
研究分野
- Life sciences Food sciences
- Life sciences Pharmacology
委員歴
- Biotechnological Research Development Association Committee Member
- Japan Society for Bioscience, Biotechnology, and Agrochemistry, JSBBA Advisory board member
- Japanese Association of Food Science and Risk Analysis Committee Member
- Japanese Society for Food Science and Technology Committee Member
- Japanese Society of Nutrition and Food Science Committee Member
受賞
- Young Researcher Encouragement Award Study on Food Functions and Bioavailablity using Functional Food Evaluation Techniques
- 2011 5th International Conference on Food Factors (ICoFF 2011) Young Investigator Award Antiproliferative activity and induction of apoptotic DNA damage by highly-lipolyzed goat cheeses
論文
Regulatory effects of antioxidants on indoxyl sulfate-enhanced intracellular oxidation and impaired phagocytic activity in differentiated U937 human macrophage cells
Exploring the potential of functional foodstuffs: Initial assessment of grape leaves and immature fruits cultivated in Minamiaso, Aso, Kumamoto, Japan
Determination of acetaminophen O-sulfate and tyrosine O-sulfate by high-performance liquid chromatography with UV detection
Investigation of radical scavenging effects of acetaminophen, p-aminophenol and their O-sulfated conjugates.
Total phenolic content and antioxidant activity of perilla pomace produced in Kumamoto: Comparative evaluation with ground sesame seeds
Chemical Synthesis of Acetaminophen O-Sulfate
Investigation of Total Polyphenol Content, Antioxidant Activity, and Carbohydrate-hydrolyzing Enzyme Inhibition of Yacon Leaves among Four Domestic Cultivars and a Peru Line for over Four Years
Development of a unique processed food using roasted Jerusalem Artichoke (Helianthus tuberosus) cultivated at Kumamoto-Minamiaso in Japan
Effects of indole and indoxyl on the intracellular oxidation level and phagocytic activity of differentiated HL-60 human macrophage cells
Investigation of the effects of indoxyl sulfate, a uremic toxin, on the intracellular oxidation level and phagocytic activity using an HL-60-differentiated human macrophage cell model.
Effect of heat processing with pressure on antioxidant activity of Makomotake cultivated at Minamiaso, Aso, Kuamamoto in Japan
Increased phenolic content and antioxidant capacity of the heated leaves of yacon (Smallanthus sonchifolius).
Effect of heat processing with pressure on inulin contents and antioxidant capacity of Jerusalem Artichoke (Helianthus tuberosus) cultivated at Kumamoto-Minamiaso in Japan
Optimization of hot-water extraction of dried yacon herbal tea leaves: Enhanced antioxidant activities and total phenolic content by response surface methodology
Radical scavenging effects of 1-naphthol, 2-naphthol, and their sulfate-conjugates.
Unique antioxidant effects of herbal leaf tea and stem tea from Moringa oleifera L. especially on superoxide anion radical generation systems.
Total polyphenol and rutin contents, and antioxidant capacity of native Kugino-zairai buckwheat cultivated in Kumamoto-Aso area: Comparison with rutin-rich SunRutin and commercial Kitawase-soba cultivars
Effect of two-step heat processing on the antioxidant activity and phenolic constituents of leaves from yacon cultivated in Kumamoto
Effects of Hot-water Extract of Herbal Tea Leaves from Yacon (Smallanthus sonchifolius): Lipoxygenase Inhibition and Suppression on Nitric Oxide Generation in RAW264.7 Mouse Macrophage-like Cells
In vitro α-glucosidase and α-amylase inhibitory effects of herbal tea leaves from Yacon (Smallanthus sonchifolius)
In vitro anti-inflammatory effects of edible Igusa soft rush (Juncus effusus L.) on lipoxygenase, hyaluronidase, and cellular nitric oxide generation assays: Comparison with Matcha green tea (Camellia sinensis L.)
In Vitro α-Amylase and α-glucosidase inhibitory effects of edible soft rush (Juncus effusus L.)
Antioxidant Effects of Herbal Tea Leaves from Yacon (Smallanthus sonchifolius) on Multiple Free Radical and Reducing Power Assays, Especially on Different Superoxide Anion Radical Generation Systems
Inhibitory effects of the ethyl acetate extract from bulbs of Scilla scilloides on lipoxygenase and hyaluronidase activities.
Homoisoflavones as the antioxidants responsible from bulbs of Scilla scilloides.
Anti-inflammatory and antioxidative effects of a methanol extract from bulbs of Scilla scilloides.
Determination of 1,1-diphenyl-2-picrylhydrazyl radical scavenging capacity and total phenolic content in four different igusa cultivars in Japan
Induction of Nitric Oxide Generation by Various Cow Milk Cheeses in RAW264.7 Mouse Macrophage-like Cells
Effect of highly lipolyzed goat cheese on HL-60 human leukemia cells: Antiproliferative activity and induction of apoptotic DNA damage
Scavenging effects of commercial goat cheeses on hydrogen peroxide and superoxide anion radical assays
Sulfation of chlorotyrosine and nitrotyrosine by human lung endothelial and epithelial cells: Role of the human SULT1A3
Effects of highly ripened cheeses on HL-60 human leukemia cells: Antiproliferative activity and induction of apoptotic DNA damage
Concerted action of the cytosolic sulfotransferase, SULT1A3, and catechol-O-methyltransferase in the metabolism of dopamine in SK-N-MC human neuroblastoma cells
A novel hydroxysteroid-sulfating cytosolic sulfotransferase, SULT3 ST3, from zebrafish: Identification, characterization, and ontogenic study
Cigarette smoke toxicants as substrates and inhibitors for human cytosolic SULTs
Hydroxylated serotonin and dopamine as substrates and inhibitors for human cytosolic SULT1A3.
Generation and release of nitrotyrosine O-sulfate by HepG2 human hepatoma cells upon SIN-1 stimulation: Identification of SULT1A3 as the enzyme responsible
Identification of novel hydroxysteroid-sulfating cytosolic SULTs, SULT2 ST2 and SULT2 ST3, from zebrafish: Cloning, expression, characterization, and developmental expression
Tissue-specific distribution of genistein, daidzein and bisphenol A in male Sprague-Dawley rats after intragastric administration
Identification of a novel thyroid hormone-sulfating cytosolic sulfotransferase, SULT1 ST5, from zebrafish: Molecular cloning, expression, characterization and ontogenic study
Identification of a novel estrogen-sulfating cytosolic SULT from zebrafish: Molecular cloning, expression, characterization, and ontogeny study
Oral contraceptives as substrates and inhibitors for human cytosolic SULTs
Suppressive effects of ascorbate derivatives on ultraviolet-B-induced injury in HaCaT human keratinocytes
Simultaneous determination of isoflavones and bisphenol A in rat serum by high-performance liquid chromatography coupled with coulometric array detection
Oral administration of soy isoflavones and determination of serum isoflavone levels in Sprague-Dawley rats
Dietary Effect of Ginkgo Biloba and Bamboo Extract Powders on Lipid Metabolism and Immune Function of Sprague-Dewley Rats
書籍等出版物
- Handbook of cheese in health: Production, nutrition and medical sciences
- Handbook on Cheese: Production, Chemistry and Sensory Properties (Agriculture Issues and Policies: Food Science and Technology)
講演・口頭発表等
- Evaluation of Cytotoxicity and Human Serum Albumin-Binding Capacity of Indoxyl, Indoxyl Sulfate and Indoxyl β-Glucuronide
- Investigation of the Inhibitory Effects of Resin Glycosides from the Seeds of Ipomoea muricata and Pharbitidis Semen on the Digestive Enzymes In Vitro
- Challenge in the Chemical Synthesis of Tyramine O-Sulfate
- Effects of p-Cresyl Sulfate and p-Cresol Glucuronide on Lipopolysaccharide-Induced Nitric Oxide Production in RAW264.7 Mouse Macrophage Cells
- Exploring antioxidant properties of yacon leaf herbal tea as a health food in Japan
- Profiling study of excellent cultivars and lines of domestic yacon leaves with high polyphenol content and antioxidant activity
- On the suppression of HL-60 human leukocyte cell growth by indoxyl sulfate: regulatory effect with a representative antioxidant, Trolox
- Antiproliferative effect of a resin glycoside fraction from Calystegia japonica on HL-60 human promyelocytic leukemia cells
- Effect of p-cresyl sulfate on the intracellular oxidation levels of HL-60-differentiated macrophage cells under oxidative stress: concerted actions with hydrogen peroxide and nitric oxide
- Determination of acetaminophen O-sulfate and tyrosine O-sulfate by high-performance liquid chromatography with UV detection
- On the multifunctional properties of 37 different soft rush grown in Japan: in vitro evaluation and multivariate analysis
- Cholinesterase inhibition by hot-water extracts from 21 different leaves of yacon cultivated in 2022 in Aso area
- Investigation of antioxidant activities of Phase-II sulfated compounds. In Symposium 5: Phase II conjugation reactions involved in the regulation of biologically active molecules
- Antioxidant effects of herbal tea from yacon leaves as a healthy drink in Japan
- Investigation of Radical Scavenging Effects of Acetaminophen, p-Aminophenol and Their O-Sulfated Conjugates
- Investigation of Total Polyphenol Content, Antioxidant Activity, and Carbohydratehydrolyzing Enzyme Inhibition of Yacon Leaves among Four Domestic Cultivars and a Peru Line for over Four Years
- Investigation of the Effect of Indoxyl Sulfate, a Uremic Toxin, on the Phagocytic Activity Using an HL-60-differentiated Human Macrophage Cell Model
- Development of Chemical Synthesis for Acetaminophen O-Sulfate
- Investigation of the Effect of Indoxyl Sulfate, a Uremic Toxin, on the Intracellular Oxidation Level Using an HL-60-differentiated Human Macrophage Cell Model
- Increased Phenolic Parameters;Antioxidant Capacities in;Heated Leaves of Yacon;Smallanthus sonchifolius)
- On the Promotion of Cellular Oxidation and Suppression of Phagocytosis by Indoxyl Sulfate, an Uremic Toxin from Tryptophan, in Human Macrophage Model Cells
- On hot-water extraction of Japanese yacon herbal tea intended for drinking: optimization of higher antioxidant activities and total phenol content by response surface methodology
- Challenge of Acetaminophen O-Sulfate Synthesis by an Established Method for Organic Synthesis of Tyrosine O sulfate
- Evaluation of Antioxidant Activity and Human Serum Albumin Binding Capacity of Uremic Toxin Indoxyl Sulfate and Its Related Metabolites
- Total Phenol Content and Different Antioxidant Activities of Yacon Herbal Tea: Optimization of Extraction Conditions by Multi-factor Response Surface Methodology
- In vitro α-Glucosidase and α-Amylase Inhibitory Effects of the Hot-water Extract of Tea Leaves from Camellia Japonica Cultivated in Kumamoto-Aso Area
- Effect of Two-step Heat Processing on the Antioxidant Activity and Phenolic parameters of Leaves from Yacon Cultivated in Kumamoto, Japan
- Antioxidant effects of herbal tea leaves from Yacon (Smallanthus sonchifolius) on multiple free radical assays (Invited)
- Comparison of phenolic parameters and inhibitory effects of yacon leaves from different varieties on carbohydrate digestive enzymes
- Inhibitory effect of 4-methylumbelliferyl sulfate on superoxide anion radical generation assays
担当経験のある科目
- Functional Food Chemistry 1 (Graduate)
- Food Chemistry (Undergraduate)
- Food Science (Undergraduate)
- Food Processing (Undergraduate)
- Functional Food Chemistry 2 (Graduate)
- Food Hygiene (Undergraduate)
所属学会
- Japan Association of Food Preservation Scientists
- Japanese Association of Food Science and Risk Analysis
- Biotechnological Research Development Association
- JAPAN SOCIETY OF NUTRITION AND FOOD SCIENCE
- JAPANESE SOCIETY FOR FOOD SCIENCE AND TECHNOLOGY
- JAPANESE DAIRY SCIENCE ASSOCIATION
- JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY
- Japanese Association for Biological Function Research
共同研究・競争的資金等の研究課題
Basic study of methods for synthesis of sulfated phenols and of quantitative assessment with metabolite activity upon sulfation
Basic research for the development of laxatives using resin glycosides as lead compounds
Study on physiological role of sulfation metabolism: challenges on the synthesis of phenolic sulfates and functional evaluation
Study on the resin glycosides for aimed to develop new medicine
Study for functionality of sulfo-conjugated phenolic metabolites
Studies on the various biological functions of the edible plants at the molecular level
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