安田 伸

Yasuda Shin

  • 教授
  • 学位:博士(農学)

基本情報

所属

  • Undergraduate School of Agriculture / Department of Bioscience
  • Graduate School of Bioscience / Course of Bioscience
  • Graduate School of Agriculture / Course of Agricultural Sciences

研究と関連するSDGs

  • Good Health and Well-Being
  • Responsible Consumption and Production

詳細情報

研究キーワード

  • Health Food
  • Functional Food Science
  • Drug Metabolism Chemistry
  • Food Biochemistry
  • Drug Metabolism

研究分野

  • Life sciences Food sciences
  • Life sciences Pharmacology

委員歴

  • Biotechnological Research Development Association Committee Member
  • Japanese Association of Food Science and Risk Analysis Committee Member
  • Japanese Society for Food Science and Technology Committee Member
  • Japanese Society of Nutrition and Food Science Committee Member

受賞

  • Young Researcher Encouragement Award Study on Food Functions and Bioavailablity using Functional Food Evaluation Techniques
  • 2011 5th International Conference on Food Factors (ICoFF 2011) Young Investigator Award Antiproliferative activity and induction of apoptotic DNA damage by highly-lipolyzed goat cheeses

論文

Effects of indole and indoxyl on the intracellular oxidation level and phagocytic activity of differentiated HL-60 human macrophage cells.

Investigation of the effects of indoxyl sulfate, a uremic toxin, on the intracellular oxidation level and phagocytic activity using an HL-60-differentiated human macrophage cell model

Optimization of hot-water extraction of dried yacon herbal tea leaves: Enhanced antioxidant activities and total phenolic content by response surface methodology

Increased phenolic content and antioxidant capacity of the heated leaves of yacon (Smallanthus sonchifolius)

Radical scavenging effects of 1-naphthol, 2-naphthol, and their sulfate-conjugates

Unique antioxidant effects of herbal leaf tea and stem tea from Moringa oleifera L. Especially on superoxide anion radical generation systems

In vitro anti-inflammatory effects of edible Igusa soft rush (Juncus effusus L.) on lipoxygenase, hyaluronidase, and cellular nitric oxide generation assays: Comparison with Matcha green tea (Camellia sinensis L.)

Antioxidant Effects of Herbal Tea Leaves from Yacon (Smallanthus sonchifolius) on Multiple Free Radical and Reducing Power Assays, Especially on Different Superoxide Anion Radical Generation Systems

Inhibitory effects of the ethyl acetate extract from bulbs of Scilla scilloides on lipoxygenase and hyaluronidase activities

Health beneficial effects of anthocyanins from purple colored crops such as sweet potato

Multifaceted functions of cheese: Anticancer effects on human leukemic cell growth in vitro

Anti-inflammatory and antioxidative effects of a methanol extract from bulbs of Scilla scilloides

Homoisoflavones as the antioxidants responsible from bulbs of Scilla scilloides

Induction of Nitric Oxide Generation by Various Cow Milk Cheeses in RAW264.7 Mouse Macrophage-like Cells

Effect of highly lipolyzed goat cheese on HL-60 human leukemia cells: Antiproliferative activity and induction of apoptotic DNA damage

Sulfation of chlorotyrosine and nitrotyrosine by human lung endothelial and epithelial cells: Role of the human SULT1A3

Effects of highly ripened cheeses on HL-60 human leukemia cells: Antiproliferative activity and induction of apoptotic DNA damage

Concerted action of the cytosolic sulfotransferase, SULT1A3, and catechol-O-methyltransferase in the metabolism of dopamine in SK-N-MC human neuroblastoma cells

A novel hydroxysteroid-sulfating cytosolic sulfotransferase, SULT3 ST3, from zebrafish: Identification, characterization, and ontogenic study

Cigarette smoke toxicants as substrates and inhibitors for human cytosolic SULTs

Hydroxylated serotonin and dopamine as substrates and inhibitors for human cytosolic SULT1A3.

Generation and release of nitrotyrosine O-sulfate by HepG2 human hepatoma cells upon SIN-1 stimulation: Identification of SULT1A3 as the enzyme responsible

Identification of novel hydroxysteroid-sulfating cytosolic SULTs, SULT2 ST2 and SULT2 ST3, from zebrafish: Cloning, expression, characterization, and developmental expression

Tissue-specific distribution of genistein, daidzein and bisphenol A in male Sprague-Dawley rats after intragastric administration

Identification of a novel thyroid hormone-sulfating cytosolic sulfotransferase, SULT1 ST5, from zebrafish: Molecular cloning, expression, characterization and ontogenic study

Identification of a novel estrogen-sulfating cytosolic SULT from zebrafish: Molecular cloning, expression, characterization, and ontogeny study

Oral contraceptives as substrates and inhibitors for human cytosolic SULTs

Simultaneous determination of isoflavones and bisphenol A in rat serum by high-performance liquid chromatography coupled with coulometric array detection

Suppressive effects of ascorbate derivatives on ultraviolet-B-induced injury in HaCaT human keratinocytes

講演・口頭発表等

  • ヤーコンハーブティーの熱水抽出における応答曲面計画法を用いた高抗酸化活性および総フェノール高含有量を目指した条件の最適化
  • 食事性タンパク質由来代謝物indoxyl sulfateの好中球細胞酸化促進作用
  • 熊本県産イグサ2品種のポリフェノール含量と抗酸化力の比較
  • ヤーコン(Smallanthus sonchifolius)葉部からの加熱茶葉の調製と製茶加工前後におけるフェノール性成分の変化
  • 解熱鎮痛薬Acetaminophen由来代謝物の強力な1,1‐Diphenyl‐2‐picrylhydrazyl(DPPH)ラジカル消去活性:類似化合物間での比較評価
  • 食用イグサ抽出物のOxygen Radical Absorbance Capacity(ORAC)法に基づく調製と総抗酸化力の評価
  • 1‐Naphtholと2‐Naphtholのフリーラジカル消去能における硫酸抱合化の影響
  • 紫芋焼酎粕を原料とする機能性飲料および食品開発
  • ヤーコン茶葉熱水抽出物のin vitroでのα-グルコシダーゼおよびα-アミラーゼ阻害作用
  • HL60ヒト白血病細胞の増殖に及ぼすチーズ抽出物の抑制作用 活性成分の分離、精製および同定
  • Oral administration of soy isoflavones and determination of serum isoflavone levels in Sprague-Dawley rats.
  • ヒト表皮細胞(HaCaT細胞)の紫外線誘導アポトーシスとその制御

所属学会

  • Japanese Association of Food Science and Risk Analysis
  • Biotechnological Research Development Association
  • JAPAN SOCIETY OF NUTRITION AND FOOD SCIENCE
  • JAPANESE SOCIETY FOR FOOD SCIENCE AND TECHNOLOGY
  • JAPANESE DAIRY SCIENCE ASSOCIATION
  • JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY
  • Japanese Association for Biological Function Research

共同研究・競争的資金等の研究課題

Study on physiological role of sulfation metabolism: challenges on the synthesis of phenolic sulfates and functional evaluation

Study for functionality of sulfo-conjugated phenolic metabolites

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