金森 審子

Kanamori Akiko

  • 教授
  • 学位:理学博士

基本情報

所属

  • Undergraduate School of Engineering / Department of Bioengineering
  • Undergraduate School of Engineering / Department of Applied Biochemistry
  • Graduate School of Engineering / Course of Applied Science

詳細情報

研究キーワード

  • glutathione
  • Metastasis
  • Tumor
  • Cell adhesion
  • Sialic acid
  • Glycoconjugate

研究分野

  • Life sciences Functional biochemistry
  • Life sciences Structural biochemistry

委員歴

  • The Japanese Biochemical Society Honorary Member

論文

Antioxidative and Antiglycative Stress Activities of Selenoglutathione Diselenide

講演・口頭発表等

  • Analysis of Novel Production Mechanism of Reduced Selenoglutathione and Its Application to Detoxification of Glycative Stress-Causing Substance
  • Detoxification of Glycative Stress-Causing Substance Using a Novel Non-Enzymatic Production Mechanism of Reduced Selenoglutathione
  • Analysis of reactivity of a glycosylated glutathione derivative with chemicals causing contact dermatitis
  • Analysis of reactivity of a glycosylated glutathione derivative, which is not degraded by gamma-glutamyltranspeptidase, with chemicals causing contact dermatitis
  • Regulating of redox balance in cells by using a water-soluble cyclic diselenide and its amphiphilic derivatives with glutathione peroxidase-like activity
  • Analysis and application of a glycosylated glutathione derivative which has resistance against degradation by gamma-glutamyltranspeptidase
  • Addition of selenoglutathione to culture medium of the cells where the expression level of glyoxalase 1 is suppressed can restore the resistance to both glycation and oxidative stress
  • Effects of selenoglutathione on the recovery of resistance to both glycation and oxidative stress of the cells suppressed their expression levels of glyoxalase 1

担当経験のある科目

  • Medical Science
  • Basic Chemistry
  • Bioinorganic Chemistry
  • Cell Biology

共同研究・競争的資金等の研究課題

Application of selenocysteine for enhancement of the reactivity of the enzymes related on redox regulation system

Mechanisms involved in the induction of cell adhesion by hypoxia inducible factor

Studies on effect of hypoxia inducible factor on cell adhesion

Study of the regulation mechanism of cell adhesion caused by a nobel modification of sialic acid

Transcriptional and post-translational regulation of cell adhesion mediated by the cell adhesion molecule, selectin, on lymphocytes.

Joint Research on Polysialo- and PolyKDN-Glycoconjugates

Development of Sensitive Probes for Deaminated Neuraminic Acid (KDN) to Search for KDN-Glycoconjugates

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