和田 健彦

Wada Takehiko

  • 准教授
  • 学位:博士(医学)

基本情報

所属

  • Undergraduate School of Medicine / Faculty of Medicine
  • Graduate School of Medicine / Course of Advanced Medical Science
  • Graduate School of Medicine / Course of Medical Science

詳細情報

研究キーワード

  • cell cycle
  • onconephrology
  • focal segmental glomerulosclerosis
  • chronic glomerulonephritis
  • water and electrolyte disorders
  • podocyte
  • nephrotic syndrome
  • Nephrology

研究分野

  • Life sciences Nephrology

委員歴

  • Japanese Society of Nephrology Councilor

受賞

  • National Kidney Foundation Young Investigator Research Grant Response to Podocytes to Injury

論文

De novo posttransplant membranous nephropathy after COVID-19 vaccination 9 years after renal transplantation in a patient with polycystic kidney disease.

Association of serum sodium levels with fractures and mortality in patients undergoing maintenance hemodialysis.

Preference for anti-phospholipase A2 receptor antibody assay in patients with suspected membranous nephropathy: a survey study on medical practice after publication of Japanese Guidelines for Nephrotic Syndrome 2020.

Japanese clinical practice patterns of rituximab treatment for minimal change disease in adults 2021: A web-based questionnaire survey of certified nephrologists.

A Case of Glomerular Microangiopathy-like Nephropathy Caused by Hyperthyroidism.

Practice patterns of rituximab for primary membranous nephropathy 2021 in Japan: a web-based survey of board-certified nephrologists.

Syphilis-related Membranous Nephropathy in a 35-year-old Woman.

Demographics and treatment of patients with primary nephrotic syndrome in Japan using a national registry of clinical personal records.

Japanese clinical practice patterns of primary nephrotic syndrome 2021: a web-based questionnaire survey of certified nephrologists.

Evaluation of ABCG2-mediated extra-renal urate excretion in hemodialysis patients.

Serum sclerostin levels and mortality in hemodialysis patients: An 8-year prospective study.

Enhanced podocyte differentiation and changing drug toxicity sensitivity through pressure-controlled mechanical filtration stress on a glomerulus-on-a-chip.

Potential progression biomarkers of diabetic kidney disease determined using comprehensive machine learning analysis of non-targeted metabolomics.

書籍等出版物

  • Evidence-based Clinical Practice Guidelines for CKD 2023
  • Nephrology for Board-Ceartified Nephrologists
  • Nephrology : text for professional

講演・口頭発表等

  • Circulating Permeability Factors in FSGS: Is suPAR a culprit?

所属学会

  • Japanese Society of Laboratory Medicine
  • International Society of Nephrology
  • American Society of Nephrology
  • Japanese Society of Dialysis Therapy
  • Japanese Society of Nephrology

共同研究・競争的資金等の研究課題

Regulating mechanisms of podocyte differentiation by vitamin D receptor signaling

Development of novel therapies for diabetic nephropathy based on the maintenance of differentiation in podocytes

Study of the molecular mechanism of podocyte protection effect with the vitamin D receptor and establishment of the new treatment base

Metabolic Reprogramming and Hypoxic Memory in Kidney Disease

Establishment of whole exome sequencing for the diagnosis of atypical hemolytic uremic syndrome

Mechanisms of maintenance of podocyte cytoskeletal structure against metabolic stress associated with diabetes and Development of novel therapeutic strategies

Regulation of hypoxia inducible genes in chronic kidney disease

Identification of microRNA that regulates renal pathophysiology related to hypoxia and ER stress

The analysis of the pathophysiology of the Kidney- Gut interaction, the vicious cycle in Chronic kidney disease and dysbiosis.

Elucidation of the pathogenesis of kidney disease via epigenetic responses against hypoxia

Elucidation of the mechanisms of podocyte homeostasis and development of new therapeutic strategies against diabetic kidney disease

Expression profile of miRNA in chronic kidney disease and identification of miRNA regulating hypoxia and endoplasmic reticulum stress signals

Elucidation of the pathophysiology of chronic kidney disease by comprehensive analysis of the hypoxia-responsive transcriptional network

Elucidation of the mechanisms underlying podocyte injury through endoplasmic reticulum stress and Development of novel therapeutic strategies for glomerular diseases

Comprehensive functional analysis and application of responses against hypoxia in the kidney

Pathophysiological contribution of endoplasmic reticulum stress in the kidney

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