谷口 俊恭

Taniguchi Toshiyasu

  • 教授
  • 学位:博士(医学)

基本情報

所属

  • Undergraduate School of Medicine / Faculty of Medicine
  • Graduate School of Medicine / Course of Advanced Medical Science
  • Graduate School of Medicine / Course of Medical Science

研究と関連するSDGs

  • Good Health and Well-Being

詳細情報

研究キーワード

  • BRCA1/2
  • drug resistance
  • Fanconi anemia
  • cancer
  • DNA repair

研究分野

  • Life sciences Medical biochemistry

論文

Maintenance of R-loop structures by phosphorylated hTERT preserves genome integrity.

RFWD3 and translesion DNA polymerases contribute to PCNA modification-dependent DNA damage tolerance.

REV1-POL ζ Inhibition and Cancer Therapy.

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.

Recent insights into the molecular basis of Fanconi anemia: genes, modifiers, and drivers

Ubiquitination-Linked Phosphorylation of the FANCI S/TQ Cluster Contributes to Activation of the Fanconi Anemia I/D2 Complex

DGCR8 Mediates Repair of UV-Induced DNA Damage Independently of RNA Processing

NEK8 regulates DNA damage-induced RAD51 foci formation and replication fork protection

Synthetic lethality: the road to novel therapies for breast cancer

BRCA1(185delAG) tumors may acquire therapy resistance through expression of RING-less BRCA1

Ataxia-Pancytopenia Syndrome Is Caused by Missense Mutations in SAMD9L

FANCI Regulates Recruitment of the FA Core Complex at Sites of DNA Damage Independently of FANCD2.

FANCI Regulates Recruitment of the FA Core Complex at Sites of DNA Damage Independently of FANCD2

p53 Is Positively Regulated by miR-542-3p

The Fanconi anemia-BRCA pathway and chemoresistance of cancer cells

Systematic screen identifies miRNAs that target RAD51 and RAD51D to enhance chemosensitivity.

53BP1 expression in sporadic and inherited ovarian carcinoma: Relationship to genetic status and clinical outcomes

MicroRNAs and DNA damage response Implications for cancer therapy

MiR-96 Downregulates REV1 and RAD51 to Promote Cellular Sensitivity to Cisplatin and PARP Inhibition

Molecular Scores to Predict Ovarian Cancer Outcomes: A Worthy Goal, but Not Ready for Prime Time

共同研究・競争的資金等の研究課題

The novel roles of microRNA biogenesis factors in DNA repair

Regulation of the Fanconi anemia-BRCA pathway

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