Ohtsuka Masato

論文

Molecular and genetic evidence for the role of AMBRA1 in suppressing S-phase entry and tumorigenesis.

Channel synapse mediates neurotransmission of airway protective chemoreflexes.

Targeted insertion of conditional expression cassettes into the mouse genome using the modified i-PITT

In vivo functional significance of direct physical interaction between Period and Cryptochrome in mammalian circadian rhythm generation

A single microRNA miR-195 rescues the arrested B cell development induced by EBF1 deficiency

Abcb4-defect cholangitis mouse model with hydrophobic bile acid composition by in vivo liver-specific gene deletion

PTBP1 protects Y RNA from cleavage leading to its apoptosis-specific degradation.

Recent Advances in the Production of Genome-Edited Animals Using <i>i</i>-GONAD, a Novel <i>in vivo</i> Genome Editing System, and Its Possible Use for the Study of Female Reproductive Systems

Bone marrow-derived fibroblast migration via periostin causes irreversible arthrogenic contracture after joint immobilization.

Delivering mRNAs to mouse tissues using the SEND system.

Improved Genome Editing via Oviductal Nucleic Acids Delivery (i-GONAD): Protocol Steps and Additional Notes.

Multiplexed genome editing by in vivo electroporation of Cas9 ribonucleoproteins effectively induces endometrial carcinoma in mice.

CRISPR-KRISPR: a method to identify on-target and random insertion of donor DNAs and their characterization in knock-in mice.

Gender-Difference in Hair Length as Revealed by Crispr-Based Production of Long-Haired Mice with Dysfunctional FGF5 Mutations.

Prototype mouse models for researching SEND-based mRNA delivery and gene therapy.

Use of anti-inhibin monoclonal antibody for increasing the litter size of mouse strains and its application to i-GONAD.

Cyclin D1 Binding Protein 1 Responds to DNA Damage through the ATM-CHK2 Pathway.

Dll1 Can Function as a Ligand of Notch1 and Notch2 in the Thymic Epithelium.

GONAD: A new method for germline genome editing in mice and rats.

共同研究・競争的資金等の研究課題

Analysis of genomic DNA in aging heart

Development of Organ- and Cell-specific In Vivo Genome Editing Technique as a Novel Approach for Cancer Gene Therapy

Development of Organ- and Cell-specific In Vivo Genome Editing Technique as a Novel Approach for Cancer Gene Therapy

Determination of chronic or intractable mechanisms induced by low bone quality with osteomacs and bone marrow derived stem cells interaction

Establishment of a next-generation impact assessment tool for low-concentration chemical exposure using THA rats

Understanding of pathophysiology and development of treatment strategy for MRONJ based on the hierarchical structure of macrophages

Understanding of pathophysiology and establishment of new treatment strategy by determining the hierarchy of macrophages in medication-related osteonecrosis of the jaw

Establishment of gene expression control system by modification of introns and its application to analysis of diabetes-related gene functions

Establishment of gene expression system by intron modification and its application for the functional analysis of diabetes-related genes

Development of novel genome editing tool for gene therapy and its application to cancer therapy

Generation of gene modified mice using in situ genome editing system without microinjection

Molecular targeted therapy for MRONJ

Identification of miRNA which rescues EBF1 deficiency indispensable for B cell lineage commitment