宮沢 正樹

Miyazawa Masaki

  • 講師
  • 学位:博士(医学)

基本情報

所属

  • Undergraduate School of Health Studies / Department of Health Management
  • Micro/Nano Technology Center

ジャンル

  • Cancer Treatment
  • Drugs
  • Traditional Chinese Medicine
  • Lifestyle-Related Diseases
  • Biotechnology

研究と関連するSDGs

  • Good Health and Well-Being

詳細情報

研究キーワード

  • Cellular Iron Metabolism
  • Cancer
  • Age-related Diseases

研究分野

  • Life sciences Molecular biology
  • Life sciences Tumor biology
  • Life sciences Nutrition and health science
  • Life sciences Pharmaceuticals - chemistry and drug development

論文

Transplantation of Fibroblast Sheets with Blood Mononuclear Cell Culture Exerts Cardioprotective Effects by Enhancing Anti-Inflammation and Vasculogenic Potential in Rat Experimental Autoimmune Myocarditis Model.

Iron-induced transferrin receptor-1 mRNA destabilization: A response to "Neither miR-7-5p nor miR-141-3p is a major mediator of iron-responsive transferrin receptor-1 mRNA degradation".

Iron metabolism and its regulatory mechanisms

Perturbation of Iron Metabolism by Cisplatin through Inhibition of Iron Regulatory Protein 2.

Regulation of transferrin receptor-1 mRNA by the interplay between IRE-binding proteins and miR-7/miR-141 in the 3'-IRE stem-loops.

Endogenous reactive oxygen species cause astrocyte defects and neuronal dysfunctions in the hippocampus: a new model for aging brain

Siderophores in Iron Metabolism: From Mechanism to Therapy Potential

Infertility and recurrent miscarriage with complex II deficiency-dependent mitochondrial oxidative stress in animal models

Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease

A Combination of Mitochondrial Oxidative Stress and Excess Fat/Calorie Intake Accelerates Steatohepatitis by Enhancing Hepatic CC Chemokine Production in Mice

Oxidative Stress Induced Inflammation Initiates Functional Decline of Tear Production (vol 7, e45805, 2012)

Distinct regulatory mechanisms of the human ferritin gene by hypoxia and hypoxia mimetic cobalt chloride at the transcriptional and post-transcriptional levels

ミトコンドリア複合体II電子伝達異常に起因する酸化ストレスと生体の加齢変容

Evidence for a novel antioxidant function and isoform-specific regulation of the human p66Shc gene

Genetically induced oxidative stress in mice causes thrombocytosis, splenomegaly and placental angiodysplasia that leads to recurrent abortion

Model animals for the study of oxidative stress from complex II

Model animals for the study of oxidative stress from complex II.

Oxidative Stress Induced Inflammation Initiates Functional Decline of Tear Production

講演・口頭発表等

  • The possibility of cancer therapy targeting to iron metabolism
  • シスプラチンによる鉄代謝異常を介した癌細胞死メカニズム
  • 電子伝達系異常酸化ストレスによる自然免疫応答と大細胞肺がん
  • シスプラチンによる鉄代謝を介した新たながん細胞死のメカニズム
  • ミトコンドリア電子伝達系傷害に伴う慢性的酸化ストレス負荷による脳内グリア環境の加齢変化
  • ミトコンドリア由来酸化ストレスによる脂肪性肝炎の線維化促進機序の解明
  • ミトコンドリア酸化ストレスによる脳内グリア環境の加齢変化
  • p66Shcの抗酸化機能とNrf2‐ARE細胞防御システムによる転写制御
  • 高LET放射線のトラック構造検出のためのDNA酸化損傷8‐OHdG可視化方法の開発
  • Evaluation of high-LET damage by measuring 8-OHdG, an oxidation product of DNA
  • ミトコンドリア酸化ストレスと加齢性角膜障害
  • ミトコンドリア由来活性酸素惹起モデルマウスを用いた酸化ストレスによる肝線維化促進機序の解明
  • Evaluation of high-LET damage by measuring 8-OHdG, an oxidation product of DNA
  • ミトコンドリア酸化ストレスによる不妊および習慣流産
  • Evaluation of high-LET damage by measuring 8-OHdG, an oxidation product of DNA
  • ミトコンドリア電子伝達系複合体II SDHC V69E変異による酸化ストレス発生の不妊と習慣流産への影響
  • Tet‐mev‐1マウスを用いた細胞内酸化ストレスによるドライアイ発症メカニズムの解析
  • ミトコンドリア酸化ストレスの不妊症と低出生体重児出産への影響

共同研究・競争的資金等の研究課題

Development of novel therapeutics for pancreatic neuroendocrine tumor targeting microRNA

The possibility of cancer therapy targeting to cellular iron metabolism

ResearchMapへ移動します

Inquiries about coverage or research

Inquiries about coverage

Public Affairs Division Public Affairs and Communications Department

Tel. 0463-63-4670(direct dialing)