永井 竜児

Nagai Ryouji

  • 教授
  • 学位:博士(医学)

基本情報

所属

  • Undergraduate School of Agriculture / Department of Food and Life Sciences
  • Undergraduate School of Agriculture / Department of Bioscience
  • Graduate School of Bioscience / Course of Bioscience
  • Graduate School of Agriculture / Course of Agricultural Sciences

ジャンル

  • Lifestyle-Related Diseases

詳細情報

研究キーワード

  • metabolic syndrome
  • monoclonal antibody
  • atherosclerosis
  • life style-related diseases

研究分野

  • Life sciences Pathobiochemistry
  • Nanotechnology/Materials Biochemistry
  • Humanities & social sciences Home economics, lifestyle science
  • Life sciences Pathobiochemistry
  • Nanotechnology/Materials Biochemistry
  • Humanities & social sciences Home economics, lifestyle science

委員歴

  • 日本酸化ストレス学会 評議員

論文

Rapid pretreatment for multi-sample analysis of advanced glycation end products and their role in nephropathy

Protein Modification with Ribose Generates Nδ-(5-hydro-5-methyl-4-imidazolone-2-yl)-ornithine

Changes in S-(2-succinyl)cysteine and advanced glycation end-products levels in mouse tissues associated with aging

Histone functions as a cell-surface receptor for AGEs

Mitochondrial stress and glycoxidation increase with decreased kidney function

Drosera tokaiensis extract containing multiple phenolic compounds inhibits the formation of advanced glycation end-products

Intracellular Accumulation of Advanced Glycation End Products Induces Osteoblast Apoptosis Via Endoplasmic Reticulum Stress.

Glucoselysine is derived from fructose and accumulates in the eye lens of diabetic rats.

Nω -(Carboxymethyl)arginine Is One of the Dominant Advanced Glycation End Products in Glycated Collagens and Mouse Tissues.

Contribution of methylglyoxal to delayed healing of bone injury in diabetes

Antibody-based detection of advanced glycation end-products: promises vs. limitations.

Two new prenylflavonoids from Epimedii Herba and their inhibitory effects on advanced glycation end-products

Two new prenylflavonoids from Epimedii Herba and their inhibitory effects on advanced glycation end-products.

講演・口頭発表等

  • N?-(carboxymethyl)arginine is one of major advance glycation end products in glycated collagen.
  • ーカルボニルによる新たな翻訳後修飾機構の解析と老化関連疾患との関連性について
  • アンチエイジングのための抗糖化素材の開発
  • 糖による無秩序な蛋白の変性と老化
  • アンチエイジングを目指したAGE生成阻害剤の開発を目指して
  • 抗AGE抗体ライブラリーを用いたAGEsの検出および阻害剤の探索
  • 天然物を用いた生活習慣病予防の最先端研究
  • Prevention of lifestyle-related diseases by regulating the metabolism of macrophages and adipocytes.
  • Screening of AGE inhibitors by antibody library

所属学会

  • 日本抗加齢医学会
  • 日本酸化ストレス学会
  • 腎とフリーラジカル研究会
  • International Maillard Reaction Society
  • 日本メイラード学会
  • American Society for Biochemistry and Molecular Biology

共同研究・競争的資金等の研究課題

Investigation of the pathogenesis of life style-related diseases and its prevention by natural compounds.

産業財産権

  • -

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