永井 竜児

Nagai Ryoji

  • 教授
  • 学位:博士(医学)

基本情報

所属

  • Undergraduate School of Agriculture / Department of Food and Life Sciences
  • Undergraduate School of Agriculture / Department of Bioscience
  • Graduate School of Bioscience / Course of Bioscience
  • Graduate School of Agriculture / Course of Agricultural Sciences

ジャンル

  • Lifestyle-Related Diseases

詳細情報

研究キーワード

  • metabolic syndrome
  • monoclonal antibody
  • atherosclerosis
  • life style-related diseases

研究分野

  • Life sciences Pathobiochemistry
  • Nanotechnology/Materials Biochemistry
  • Humanities & social sciences Home economics, lifestyle science

委員歴

  • 日本酸化ストレス学会 評議員

論文

Light-emitting diode-induced ellagic acid production in Drosera tokaiensis inhibits advanced glycation end-product formation

Effects of genome composition on phenotypic plasticity and secondary metabolites in the amphidiploid species Drosera tokaiensis and its parent species under different monochromatic lighting

RAGE activation in macrophages and development of experimental diabetic polyneuropathy

In vitro evaluation of the anti-diabetic potential of soymilk yogurt and identification of inhibitory compounds on the formation of advanced glycation end-products

Rapid pretreatment for multi-sample analysis of advanced glycation end products and their role in nephropathy

Protein Modification with Ribose Generates Nδ-(5-hydro-5-methyl-4-imidazolone-2-yl)-ornithine

Changes in S-(2-succinyl)cysteine and advanced glycation end-products levels in mouse tissues associated with aging

Histone functions as a cell-surface receptor for AGEs

Mitochondrial stress and glycoxidation increase with decreased kidney function

Identification of acetaldehyde-modified lysine

Mass spectrometric quantitation of AGEs and enzymatic crosslinks in human cancellous bone.

Drosera tokaiensis extract containing multiple phenolic compounds inhibits the formation of advanced glycation end-products

Intracellular Accumulation of Advanced Glycation End Products Induces Osteoblast Apoptosis Via Endoplasmic Reticulum Stress.

Trapa bispinosa Roxb. and lutein ameliorate cataract in type 1 diabetic rats.

Glucoselysine is derived from fructose and accumulates in the eye lens of diabetic rats.

Nω -(Carboxymethyl)arginine Is One of the Dominant Advanced Glycation End Products in Glycated Collagens and Mouse Tissues.

Contribution of methylglyoxal to delayed healing of bone injury in diabetes

Aphanothece sacrum (Sur.) Okada Prevents Cataractogenesis in Type 1 Diabetic Mice.

書籍等出版物

  • AGEs生成阻害物質の探索研究:シャクヤクのCMA生成阻害活性成分について(2)
  • 新規糖化反応後期生成物:Nω‐(carboxyethyl)arginine(CEA)の免疫化学的な血中濃度の測定

所属学会

  • 日本酸化ストレス学会
  • 腎とフリーラジカル研究会
  • International Maillard Reaction Society
  • American Society for Biochemistry and Molecular Biology

共同研究・競争的資金等の研究課題

Exploration of new functional foods for prevention of lifestyle-related diseases, based on improvement of mitochondrial function

Investigation of alcohol toxicity and its prevention by functional food

Research on early diagnosis of abnormal carbohydrate metabolism by antibody specific for AGEs

Investigation of the pathogenesis of life style-related diseases and its prevention by natural compounds.

産業財産権

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